2005 Publications

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  • Brown NF, Vallance BA, Coombes BK, Valdez Y, Coburn BA, Finlay BB. Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine. PLoS Pathog. 2005 Nov 18;1(3):e32 [abstract]
  • Coombes BK, Wickham ME, Lowden MJ, Brown NF, Finlay BB. Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17460-5. [abstract]
  • Hsiao WW, Ung K, Aeschliman D, Bryan J, Finlay BB, Brinkman FS. Evidence of a Large Novel Gene Pool Associated with Prokaryotic Genomic Islands. PLoS Genet. 2005 Nov 18;1(5):e62 [abstract]
  • Barba J, Bustamante VH, Flores-Valdez MA, Deng W, Finlay BB, Puente JL. A positive regulatory loop controls expression of the locus of enterocyte effacement-encoded regulators Ler and GrlA. J Bacteriol. 2005 Dec;187(23):7918-30. [abstract]
  • Boyle EC, Finlay BB. Leaky guts and lipid rafts. Trends Microbiol. 2005 Dec;13(12):560-3 [abstract]
  • Orozco NM, Touret N, Zaharik ML, Park E, Kopelman R, Miller S, Finlay BB, Gros P, Grinstein S.Visualization of Vacuolar Acidification-induced Transcription of Genes of Pathogens inside Macrophages. Mol Biol Cell. 2005 Oct 26 [abstract]
  • Coombes BK, Coburn BA, Potter AA, Gomis S, Mirakhur K, Li Y, Finlay BB. Related Articles, Links Analysis of the contribution of salmonella pathogenicity islands 1 and 2 to enteric disease progression using a novel bovine ileal loop model and a murine model of infectious enterocolitis.Infect Immun. 2005 Nov;73(11):7161-9. [abstract]
  • Gauthier A, Robertson ML, Lowden M, Ibarra JA, Puente JL, Finlay BB. Transcriptional inhibitor of virulence factors in enteropathogenic Escherichia coli. Antimicrob Agents Chemother. 2005 Oct;49(10):4101-9. [abstract]
  • Rodriguez-Escudero I, Hardwidge PR, Nombela C, Cid VJ, Finlay BB, Molina M. Enteropathogenic Escherichia coli type III effectors alter cytoskeletal function and signalling in Saccharomyces cerevisiae. Microbiology. 2005 Sep;151(Pt 9):2933-45. [abstract]
  • Thomas NA, Deng W, Puente JL, Frey EA, Yip CK, Strynadka NC, Finlay BB. CesT is a multi-effector chaperone and recruitment factor required for the efficient type III secretion of both LEE- and non-LEE-encoded effectors of enteropathogenic Escherichia coli. Mol Microbiol. 2005 Sep;57(6):1762-79. [abstract]
  • Finlay BB. Bacterial virulence strategies that utilize Rho GTPases. Curr Top Microbiol Immunol. 2005;291:1-10. Review. [abstract]
  • Yip CK, Kimbrough TG, Felise HB, Vuckovic M, Thomas NA, Pfuetzner RA, Frey EA, Finlay BB, Miller SI,Strynadka NC. Structural characterization of the molecular platform for type III secretion system assembly. Nature. 2005 Jun 2;435(7042):702-7. [abstract]
  • Coburn B, Li Y, Owen D, Vallance BA, Finlay BB. Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis. Infect Immun. 2005 Jun;73(6):3219-27. [abstract]
  • Hardwidge PR, Deng W, Vallance BA, Rodriguez-Escudero I, Cid VJ, Molina M, Finlay BB. Modulation of host cytoskeleton function by the enteropathogenic Escherichia coli and Citrobacter rodentium effector protein EspG.Infect Immun. 2005 May;73(5):2586-94. [abstract]
  • Coombes BK, Wickham ME, Brown NF, Lemire S, Bossi L, Hsiao WW, Brinkman FS, Finlay BB.Genetic and molecular analysis of GogB, a phage-encoded type III-secreted substrate in Salmonella enterica serovar typhimurium with autonomous expression from its associated phage. J Mol Biol. 2005 May 13;348(4):817-30. [abstract]
  • Lupp C, Finlay BB. Intestinal microbiota. Curr Biol. 2005 Apr 12;15(7):R235-6. Review. [abstract]
  • Deng W, Li Y, Hardwidge PR, Frey EA, Pfuetzner RA, Lee S, Gruenheid S, Strynakda NC, Puente JL, Finlay BB. Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens. Infect Immun. 2005 Apr;73(4):2135-46. [abstract]
  • Coombes BK, Finlay BB. Insertion of the bacterial type III translocon: not your average needle stick.Trends Microbiol. 2005 Mar;13(3):92-5. Review. [abstract]
  • Knodler LA, Finlay BB, Steele-Mortimer O. The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt. J Biol Chem. 2005 Mar 11;280(10):9058-64. Epub 2005 Jan 10. [abstract]
  • Yip CK, Finlay BB, Strynadka NC. Structural characterization of a type III secretion system filament protein in complex with its chaperone. Nat Struct Mol Biol. 2005 Jan;12(1):75-81. [abstract]